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Decoding Autoimmunity with Dr. Datis Kharrazian

Fri, 19 Sep 2025
In this episode, I dive into the complexities of autoimmunity and the gut-brain axis with Dr. Datis Kharrazian, one of the leading voices in functional medicine. What strikes me about our conversation is how he connects the dots between environment, genetics, and lifestyle, painting a clear picture of why autoimmune diseases are on the rise and why they’re so difficult to treat.

Dr. Kharrazian breaks down how and why the immune system malfunctions, and more importantly, how lifestyle adaptations can play a pivotal role in managing these conditions. Together, we explore the principles of functional medicine and how they reshape chronic disease care, while also looking at the latest insights into the gut microbiome, its impact on brain health, and the links to conditions like Alzheimer’s and long COVID.

This episode is packed with professional insights, practical takeaways, and a vision of how functional medicine can transform patient care in today’s world.

Key Takeaways:

  • Autoimmunity occurs when the immune system mistakenly attacks the body’s own tissues, with factors such as environmental exposure and genetic susceptibility being key contributors.

  • Functional medicine prioritizes enhancing bodily functions rather than simply inhibiting disease symptoms, offering a promising approach for managing chronic diseases.

  • Lifestyle factors like sleep, stress management, and exercise play a crucial role in managing autoimmune conditions and maintaining overall health.

  • The gut-brain axis is integral to understanding and treating neurological conditions, with bidirectional communication between these systems influencing health outcomes.

  • Precision diagnostics and individualized care models are essential for effective functional medicine practice, emphasizing the need for education in the field.

Dr. Datis Kharrazian is a clinical research scientist, academic professor, and a functional medicine healthcare provider. He is an Associate Clinical Professor at Loma Linda University School of Medicine.

Dr. Kharrazian earned a PhD in Health Science with concentrations in immunology and toxicology, and a Doctor of Health Science degree from Nova Southeastern University. He also holds a Master of Science degree in Human Nutrition from the University of Bridgeport, a Doctor of Chiropractic degree from Southern California University of Health Sciences, and a Master of Medical Sciences degree in Clinical Investigation from Harvard Medical School. Dr. Kharrazian completed his post-doctoral research training at Harvard Medical School and Massachusetts General Hospital. He was a researcher at Harvard Medical School for seven years.

Currently, he serves as the academic director of the Kharrazian Institute and the Academy of Functional Nutrition and Lifestyle Medicine.

Unlocking the Secrets of Cellular Health

Fri, 12 Sep 2025
In this episode, we sit down with Dr. Ivan Rusilko, DO, CSN, PT, a medical doctor who’s redefining personalized care. We dive into the power of precision diagnostics and the urgent need for customized health protocols to optimize cellular function. You’ll get an inside look at the latest strategies transforming patient care in South Beach, where every intervention is about maximizing your body’s potential from the inside out.

Dr. Rusilko walks us through a test-and-not-guess approach to health, showing how comprehensive lab panels reveal what’s really happening at a cellular level. From peptides and NAD protocols to immune support and lifestyle interventions, this episode is packed with actionable insights that show how the right combination of cutting-edge medicine and daily habits can dramatically improve energy, immunity, and overall wellbeing.

Key Takeaways:

  • Emphasis on cellular health is crucial for aging, healing, and performance, with a focus on mitochondrial function and ATP production.

  • Diagnostic testing is non-negotiable; understanding comprehensive blood markers can guide personalized treatment plans.

  • Lifestyle factors, including sleep, nutrition, and hydration, are foundational for health optimization, underscoring the need for patient responsibility.

  • Peptides and supplements, such as NAD and BPC-157, show significant promise for mitochondrial health and immune support.

  • Strategies like intermittent fasting need nuance and moderation; extreme fasting may pose health risks by stressing the body.

More About Dr. Ivan Rusilko:

Dr. Ivan Rusilko is a distinguished professional with a diverse background encompassing international fitness modeling, collegiate athletics, bodybuilding championships, and the prestigious title of two-time Mr. USA in both 2008 and 2010. Leveraging his extensive experience, Dr. Rusilko firmly believes in the integration of lifestyle and medicine as the key to achieving a prolonged and enhanced quality of life.

Situated in the heart of Miami Beach, Dr. Rusilko’s established practice warmly welcomes individuals committed to their personal evolution. Employing a patient-centric approach, he tailors treatments based on thorough diagnostics, addressing the physical, mental, and emotional dimensions unique to each individual. Dr. Rusilko goes beyond traditional medical interventions, collaborating with patients to strike a harmonious balance between health and reality.

As the owner and founder of Lifestyle Medicine's Miami Beach, Dr. Rusilko focuses on holistic aspects of human well-being, including physicality, mentality, and emotionality, which he promotes in his personal life by leading by example. He currently hosts the Lifestyle Medicine podcast with Access Medical Labs.

Dr. Ivan Rusilko's contributions to the field have gained recognition through appearances on various podcasts and features in esteemed publications including USA Today, Playboy, Men’s Health, GQ, Muscle & Fitness, Forbes, Sports Illustrated, and the NY Post, to name a few. He is acknowledged for being the youngest physician to have revolutionized numerous treatment styles in the alternative medicine field, dating back to 2011 when he began his career at the Four Seasons Miami Institute.

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This episode is sponsored by Access Labs. Providers, streamline your diagnostics with fast, accurate results in just 24 hours. From routine labs to advanced hormones and weight management, Access Labs offers over 1,000 biomarkers plus flexible collection options for practices of any size.

Get started at www.accesslabs.com/get-started and enjoy 10% off your first invoice.

EMF Effects on Men’s Health and Fertility

Fri, 05 Sep 2025
In this eye-opening episode, I sit down with Arthur Menard de Calenge, the visionary CEO and Founder of HAVN to delve into a topic that’s often overlooked but critically important: EMF exposure and its impact on our health.

We explore how the invisible radiation emitted by everyday devices—like cell phones, laptops, and Wi-Fi routers—can affect our fertility, hormone balance, and overall well-being. Arthur shares insights from over 2,200 peer-reviewed studies linking EMF exposure to adverse health effects, including decreased sperm count and motility, DNA damage, and increased oxidative stress.

But it’s not all doom and gloom. Arthur also discusses practical steps we can take to mitigate these risks, such as maintaining distance from emitting devices, using EMF meters to measure exposure, and adopting protective measures like switching to wired headphones. He also introduces HAVN’s innovative WaveStopper™ fabric, inspired by spacesuit technology, which blocks 99.7% of EMF radiation and is incorporated into everyday clothing items like hats, underwear, and laptop pads.

This conversation is a must-listen for anyone interested in understanding the science behind EMF exposure and learning actionable strategies to protect themselves in our increasingly connected world.

Key Takeaways:

  • EMF Exposure and Health: EMF exposure can have significant adverse effects on human health, particularly male fertility, through mechanisms like increased reactive oxygen species.

  • Protective Measures: Simple everyday adjustments, such as removing cell phones from pockets and turning off Wi-Fi routers during sleep, can significantly reduce EMF exposure.

  • HAVN's Product Innovation: HAVN offers a range of clothing and accessories designed to block EMF radiation, utilizing technology inspired by space suits.

  • Scientific Support and Awareness: Over 2,200 studies have linked EMF exposure to various health risks, emphasizing the need for greater public awareness and precaution.

  • Practical Benefits for Athletes: Top athletes, including Rudy Gobert, use HAVN products to enhance recovery and performance by reducing EMF-induced stress and enhancing heart rate variability.

More About Arthur Menard de Calenge:

Arthur Menard is a Forbes 30 Under 30 entrepreneur, TEDx speaker, and the founder of HAVN (havnwear.com), the world’s first EMF-blocking apparel designed for daily wear.

Trusted by doctors, elite athletes, and the U.S. Air Force, HAVN’s patented WaveStopperTM fabric blocks 99.7% of radiation from everyday tech, helping reduce risks tied to fertility, hormones, and cognitive health.

Since launch, HAVN has sold over 250,000 products to more than 70,000 customers worldwide.

Arthur holds an MS in Biology & Engineering from AgroParisTech and an MBA from HEC Paris. His mission is to help people live longer, feel better, and thrive in a connected world.

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This episode is sponsored by Professional Co-op®, where clinicians gain exceptional access to industry-leading lab services without the hefty price tag—since 2001, they’ve been redefining what efficient, patient-focused support looks like. Imagine no hidden fees, no minimums, and only paying for completed tests. Experience lab services that not only meet but also exceed your expectations. Join the co-op trusted by countless licensed clinicians nationwide. Visit www.professionalco-op.com to learn more!

This episode is also made possible by Functional Medicine University. FMU is a fully online, self-paced training program in functional medicine, founded in 2006 by Dr. Ron Grisanti. With students in all 50 U.S. states and 68 countries globally, FMU has become a cornerstone in advanced clinical education for healthcare practitioners. The curriculum is led by Dr. Grisanti, alongside contributions from over 70 distinguished medical experts on FMU’s advisory board. Graduates earn the prestigious Certified Functional Medicine Practitioner (CFMP®) credential upon completion. FMU is also a nationally approved provider of continuing education for a wide range of licensed professionals, including MDs, DCs, DOs, NDs, acupuncturists, PAs, NPs, nurses, dietitians, pharmacists, and dentists. Whether you're looking to expand your clinical knowledge or bring a functional approach to your practice, FMU offers the tools, guidance, and certification to help you thrive. Visit www.functionalmedicineuniversity.com to learn more!

Decoding the Gut Microbiome with AI

Fri, 29 Aug 2025
The gut microbiome isn’t just about digestion, it’s the command center influencing everything from mental health and immune resilience to athletic performance and chronic disease risk. In this episode, Dr. Leo Grady unpacks the gut’s far-reaching role in human health, highlighting its intricate connections with the immune and nervous systems, nutrient processing, and hormonal regulation.

But this conversation goes beyond biology. Dr. Grady introduces cutting-edge innovations in artificial intelligence and genomic sequencing that are reshaping how we study and support the gut. From AI-driven digital twin models to precision dietary and lifestyle interventions, listeners will discover how technology is unlocking a future where gut health can be measured, predicted, and personalized like never before.

Whether you’re a clinician, health enthusiast, or simply curious about the next frontier in medicine, this episode will change the way you think about your gut and the future of healthcare itself.

Key Takeaways:

  • Every aspect of health, including metabolic disorders and mental health, is linked to the gut microbiome.

  • Jonah utilizes advanced AI and genomic sequencing to provide comprehensive gut microbiome analysis.

  • AI's ability to simulate dietary and lifestyle changes can inform personalized health interventions.

  • Shifts in gut microbiome environments indicate possible precursors to diseases like Parkinson's and Alzheimer's.

  • Personalized medicine through AI-driven insights offers an innovative approach to optimize health outcomes.

More About Dr. Leo Grady, PhD:

Dr. Leo Grady is an internationally recognized leader in applying AI to healthcare, with over 20 years of experience across pioneering startups and global medical companies. As CEO of Paige.ai, he guided the company to industry leadership, launching groundbreaking products worldwide and securing the first-ever FDA approval for an AI product in pathology.

Today, as Founder and CEO of Jona, Dr. Grady is spearheading the use of AI and digital twin technology to decode and reshape the gut microbiome, unlocking new ways to transform human health.

A prolific innovator, he has authored two books on AI, published over 100 scientific papers, and holds more than 300 patents. His work has earned him the Edison Patent Award and induction as a Fellow of the American Institute for Medical and Biological Engineering.

Dr. Grady earned his Ph.D. in Cognitive and Neural Systems from Boston University and currently also serves as CEO in Residence with Breyer Capital.

This episode is sponsored by Professional Co-op®, where clinicians gain exceptional access to industry-leading lab services without the hefty price tag—since 2001, they’ve been redefining what efficient, patient-focused support looks like. Imagine no hidden fees, no minimums, and only paying for completed tests. Experience lab services that not only meet but also exceed your expectations. Join the co-op trusted by countless licensed clinicians nationwide. Visit www.professionalco-op.com to learn more!

This episode is also made possible by Functional Medicine University. FMU is a fully online, self-paced training program in functional medicine, founded in 2006 by Dr. Ron Grisanti. With students in all 50 U.S. states and 68 countries globally, FMU has become a cornerstone in advanced clinical education for healthcare practitioners. The curriculum is led by Dr. Grisanti, alongside contributions from over 70 distinguished medical experts on FMU’s advisory board. Graduates earn the prestigious Certified Functional Medicine Practitioner (CFMP®) credential upon completion. FMU is also a nationally approved provider of continuing education for a wide range of licensed professionals, including MDs, DCs, DOs, NDs, acupuncturists, PAs, NPs, nurses, dietitians, pharmacists, and dentists. Whether you're looking to expand your clinical knowledge or bring a functional approach to your practice, FMU offers the tools, guidance, and certification to help you thrive. Visit www.functionalmedicineuniversity.com to learn more!

How Too Much Iron Wrecks Hormones and Longevity

Fri, 22 Aug 2025
Most people think iron is only a concern if they’re deficient, but too much iron can be just as dangerous. In this episode, I sit down with Dr. Christy Sutton, a leading figure in the study of iron imbalances, to explore the often-overlooked health epidemic of unrecognized iron overload. Anchored around her book, The Iron Curse, we discuss why outdated laboratory ranges often fail to detect these imbalances and why recognizing them is so crucial for long-term health.


From there, we dive into the intricacies of iron metabolism and the need for updated functional health ranges tailored to healthy populations. Dr. Sutton explains how imbalances can signal underlying health problems and highlights the value of functional lab testing in catching issues conventional methods often miss. We also explore the role of genetic testing—especially for hereditary hemochromatosis—and how genetics and environmental factors work together to influence iron levels.

Key Takeaways:

  • Iron Imbalance Epidemic: Iron imbalances, particularly overload, are often underdiagnosed due to outdated lab ranges and misconceptions, representing a silent health epidemic.

  • Functional vs. Conventional Ranges: Functional health ranges, as opposed to traditional lab ranges based on sick populations, are crucial for accurate diagnosis of iron-related health conditions.

  • Importance of Genetic Testing: Genetic factors (hemochromatosis genes) play a significant role in iron overload, necessitating comprehensive testing beyond typical lab work.

  • Dietary and Lifestyle Influences: Both high and low iron levels are influenced by diet, lifestyle, and, importantly, how iron interacts with other nutrients and lifestyle factors like exercise.

  • Gender and Iron Requirements: Iron needs differ significantly by sex and life stages, with menstrual and post-menopausal women, as well as men, needing tailored iron management strategies.

More About Dr. Christy Sutton, D.C.:

Dr. Christy Sutton is interested in asking why health problems happen and finding the safest and least problematic solutions. Her work takes a deep and meaningful dive into genomics, labs testing and creating a personalized health plan.

Her focus on finding and avoiding health landmines early stems from her personal experience with Crohn’s and celiac disease plus her husband’s experience with high iron, hemochromatosis, and a pituitary tumor that likely was associated with having undiagnosed hemochromatosis.


Connect with me!

This episode is sponsored by Professional Co-op®, where clinicians gain exceptional access to industry-leading lab services without the hefty price tag—since 2001, they’ve been redefining what efficient, patient-focused support looks like. Imagine no hidden fees, no minimums, and only paying for completed tests. Experience lab services that not only meet but also exceed your expectations. Join the co-op trusted by countless licensed clinicians nationwide. Visit www.professionalco-op.com to learn more!

This episode is also made possible by Functional Medicine University. FMU is a fully online, self-paced training program in functional medicine, founded in 2006 by Dr. Ron Grisanti. With students in all 50 U.S. states and 68 countries globally, FMU has become a cornerstone in advanced clinical education for healthcare practitioners. The curriculum is led by Dr. Grisanti, alongside contributions from over 70 distinguished medical experts on FMU’s advisory board. Graduates earn the prestigious Certified Functional Medicine Practitioner (CFMP®) credential upon completion. FMU is also a nationally approved provider of continuing education for a wide range of licensed professionals, including MDs, DCs, DOs, NDs, acupuncturists, PAs, NPs, nurses, dietitians, pharmacists, and dentists. Whether you're looking to expand your clinical knowledge or bring a functional approach to your practice, FMU offers the tools, guidance, and certification to help you thrive. Visit www.functionalmedicineuniversity.com to learn more!

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