In this episode of Peak Human, Brian Sanders sits down with physician, athlete, and author Dr. Jaime Seeman to discuss what it really takes to become "hard to kill."

Dr. Seeman is a practicing OB-GYN, former Mrs. Nebraska, competitive athlete, and metabolic health advocate. After struggling with her own metabolic issues, including prediabetes and hypothyroidism, she transformed her health through diet, strength training, and lifestyle changes.

Together, Brian and Dr. Seeman explore how metabolic dysfunction develops, why muscle is one of the most powerful tools for longevity, and why focusing on nutrients instead of calories may be the key to fixing modern health problems.

They also dive into women's metabolic health, perimenopause, visceral fat, and the role of diet evolution—from ketogenic to carnivore to a flexible real-food approach.

This conversation breaks down the science of human nutrition and performance while offering practical strategies for living stronger, longer, and healthier.

Show Notes

04:00 – Why modern medicine focuses on treatment instead of prevention

07:00 – The growing movement for metabolic health

11:00 – Diet tribes vs. real food

12:00 – Dr. Seeman's personal metabolic health journey

15:00 – Keto, carnivore, and evolving diets

18:00 – The Sapien lifestyle: eating like humans evolved to eat

20:00 – Women's hormones, carbs, and the menstrual cycle

23:00 – Fasted training and metabolic flexibility

27:00 – Nutrient density vs calorie counting

31:00 – Muscle: the most overlooked organ in medicine

33:00 – Visceral fat and hidden metabolic disease

35:00 – Beauty and nutrition

42:00 – C-sections, childbirth, and the infant microbiome

​​After a short break, Peak Human returns with a powerful conversation about one of the biggest problems in modern healthcare: the sick care system.

For decades, the system has been structured around treating illness rather than maintaining health. Incentives are misaligned across the entire industry, from insurance companies and employers to doctors and digital health startups. Despite technological advances, healthcare costs continue rising while population health declines.

In this episode, Aneil, a scientist, investor, and systems thinker, introduces a bold alternative: the Lifespan Model. Drawing on experience in biotechnology, Silicon Valley startups, digital health investing, and incentive design, Aneil explains how healthcare could be rebuilt around the simple idea that people should be rewarded for keeping others healthy.

Instead of replacing the current system overnight, the Lifespan Model proposes a parallel structure, one that aligns financial incentives with longevity, prevention, and long-term wellbeing.

If implemented, this model could transform healthcare from a trillion-dollar illness industry into a system that actually rewards health.

00:00 – Peak Human Returns & Show Updates
04:30 – Aneil's Background in Science and Startups
08:30 – Systems Thinking and Incentive Design
10:30 – Why the Healthcare System Is Broken
14:30 – The Incentive Problem in Medicine
17:00 – Employer-Based Health Insurance Issues
19:00 – Why Digital Health Hasn't Fixed Healthcare
21:00 – The Technologist's Journey Through Healthcare
23:30 – How Incentives Shape Entire Systems
26:00 – Introducing the Lifespan Model
29:30 – Learning From the Life Insurance Industry
33:00 – Aligning Financial Incentives With Health
36:30 – The Role of Lifespan Agents
40:00 – Technology's Role in Preventive Health
43:00 – Building a Parallel Health System
47:00 – Challenges to Implementing the Model
51:00 – The Future of Healthcare Incentives

In this episode, Chris and Brian discuss a range of topics as they wrap up the year 2025. They touch on personal holiday experiences, including Brian's unique gift-giving tradition of making meat chips and a humorous discussion about him giving out his phone number on Christmas. The conversation delves into Brian's recent scientific papers on food processing and nutrient energy quotient and debunking some diet myths.

SHOW NOTES:

00:47 Christmas Gifts and Traditions

 01:46 Personal Life and Fitness Goals

03:31 Brian's Cool Life in Hawaii

05:14 Boat Trip and Dating Adventures

14:44 Legacy and Scientific Contributions

24:43 Understanding Food's Impact on Health

25:58 Introducing the Nutrient Energy Quotient (NEQ)

27:28 The NEQ Scale and Its Implications

35:16 Debunking Diet Myths

39:25 Conspiracy Theories and Media Manipulation

GET BEEF TALLOW PRODUCTS http://NosetoTail.org

 FREE SAPIEN FOOD GUIDE http://sapien.org

Follow along: http://twitter.com/FoodLiesOrg

http://instagram.com/food.lies

http://facebook.com/FoodLiesOrg

In this episode of the Sapien podcast, hosts Brian Sanders and Chris Krueger discuss a range of topics including their New Year's resolutions, personal health challenges, and fitness goals. Chris shares a detailed story about a recent eye procedure and the importance of maintaining good health. They dive into the importance of sustainability in diet and lifestyle, highlighting the benefits of whole, animal-based foods and discussing the concept of healthy lifespan (HALE). The hosts also reflect on specific fitness goals, such as increasing muscle mass and maintaining relative strength, and how these contribute to long-term health. They set ambitious personal challenges for 2023, including goals for strength training, relative strength benchmarks, and maintaining a healthy diet. The episode wraps up with a reflection on the importance of maintaining healthy habits and lifestyle choices for long-term wellbeing.

 00:31 New Year's Resolutions: To Make or Not to Make?

01:49 Health Insurance and Crowd Health

06:56 Fitness Goals and Sustainable Living

08:07 Holiday Indulgence and Fitness Maintenance

20:40 The Extremity Challenge: Building Bigger Limbs 

26:01 The Real Blue Zones

28:36 Longevity and Diet

30:31 Strength and Exercise Metrics

36:16 New Year's Resolutions and Fitness Metrics

GET BEEF TALLOW PRODUCTS http://NosetoTail.org

FREE SAPIEN FOOD GUIDE http://sapien.org

Follow along: http://twitter.com/FoodLiesOrg

http://instagram.com/food.lies

http://facebook.com/FoodLiesOrg